Progenics Pharmaceuticals Inc.  (PGNX) Trade Now »     Rate PGNX  -  Discuss PGNX  -  Add to Watch List        

Filed under: Analyst reports, Analyst upgrades and downgrades, General Motors (GM), UAL Corp (UAUA)

MOST NOTEWORTHY: Concur Tech, Groupe Danone and General Motors were today's noteworthy downgrades:

• Piper downgraded shares of Concur Tech (NASDAQ: CNQR) to Neutral from Buy after transferring analyst coverage, as they believe potential upside to estimates is priced into shares while competitive concerns from American Express (NYSE: AXP) are not.
  
• Morgan Stanley downgraded shares of Groupe Danone (OTC: GDNNY) to Equal Weight from Overweight to reflect reduced visibility in the company's

StreetInsider.com Pre-Open Movers:

Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) 23% HIGHER; Progenics and Wyeth (NYSE: WYE) announced that the FDA has approved RELISTOR subcutaneous injection for the treatment of opioid-induced constipation in patients with advanced illness who are receiving palliative care, when response to laxative therapy has not been sufficient.

ISIS Pharmaceuticals Inc. (Nasdaq: ISIS) 23% LOWER; The FDA has provided guidance regarding approval requirements for mipomersen. The FDA has indicated that reduction of LDL-cholesterol is an acceptable surrogate endpoint for

Filed under: Analyst reports, Analyst upgrades and downgrades, Wal-Mart (WMT), Wendy's Intl (WEN), Northrop Grumman (NOC)

MOST NOTEWORTHY:

• Cowen upgraded Northrop Grumman (NYSE: NOC) to Outperform from Neutral following the Q1 report based on accelerating growth. Shares were also upgraded at JP Morgan to Overweight from Neutral.
  
• Friedman Billings upgraded Phase Forward (NASDAQ: PFWD) to Outperform from Market Perform following the solid Q1 report and views guidance as beatable.
  
• CIBC raised Celestica (N